A phase I study determining the safety and tolerability of combination therapy with pazopanib, a VEGFR/PDGFR/raf inhibitor, and GSK1120212, a MEK inhibitor, in advanced solid tumors enriched with patients with advanced differentiated thyroid cancer.

Authors

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Shabina Roohi Ahmed

The Johns Hopkins University School of Medicine, Baltimore, MD

Shabina Roohi Ahmed , Nilofer Saba Azad , Douglas Wilmot Ball , Michelle A. Rudek , Barry Nelkin , David Cosgrove , Jing Gong , Daniel Finkelstein , Marianna Zahurak , Filip Janku , Melinda Downs , Ashley O'Connor , Susan Markus , Michael Anthony Carducci , Steven I. Sherman , Razelle Kurzrock

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Poster Details

Meeting

2012 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics - Experimental Therapeutics

Track

Developmental Therapeutics

Sub Track

Signal Transduction

Clinical Trial Registration Number

NCT01438554

Citation

J Clin Oncol 30, 2012 (suppl; abstr TPS3117)

DOI

10.1200/jco.2012.30.15_suppl.tps3117

Abstract #

TPS3117

Poster Bd #

22C

Abstract Disclosures